List of Tests

Efficacy Evaluation of Cosmetics (Skincare) 

1. Anti-Aging Evaluation
  • In vivo test for skin wrinkles (marketing)
  • In vivo test for skin elasticity
  • In vivo test for elastic resilience
  • In vivo test for the improvement of facial sagging (cheeks, eyelids)
  • In vivo test for skin density
  • In vivo test for skin texture
2. Skin Color Evaluation
  • In vivo test for skin brightness (marketing)
  • In vivo test for skin tone uniformity
  • In vivo test for melanin in the skin
  • In vivo test for pigmentation (melasma, blemishes) improvement
3. Skin Moisture Evaluation
  • In vivo test for skin moisturization
  • In vivo test for skin moisturization durability
  • In vivo test for moisture in the skin (up to 0.5 mm)
5. Cleaning Evaluation
  • In vivo test for makeup (waste) cleaning
  • In vivo test for fine dust cleaning / in vivo test for preventing fine dust adsorption
  • In vivo test for ease of cleaning
  • In vivo test for pore cleanliness
6. Other Evaluations
  • In vivo test for skin antioxidant
  • In vivo test for skin soothing
  • In vivo test for skin barrier strengthening (recovery)
  • In vivo test for micro-blood flow
  • In vivo test for the enhancement of dead skin cell turnover
  • In vivo test for the relief of itch caused by dry skin
  • In vivo test for skin swelling (eyelids, calves, face) relief
  • In vivo test for temporary cellulite evaluation

Efficacy Evaluation of Cosmetics (UV Protection) 

SPF PA Water resistance In-vitro

MFDS

Cosmetics Europe (ISO24444)

FDA

CFDA

ASEAN

MFDS

JCIA (ISO24442)

CFDA

ASEAN

MFDS water resistance

Colipa water resistance

FDA

CFDA

ISO 24443

FDA final rule (2011)

Efficacy Evaluation of Cosmetics (Makeup) 

  • In vivo test for skin wrinkles (marketing)
  • In vivo test for skin elasticity
  • In vivo test for elastic resilience
  • In vivo test for the improvement of facial sagging (cheeks, eyelids)
  • In vivo test for skin density
  • In vivo test for skin texture

Efficacy Evaluation of Cosmetics (Hair) 

  • In vivo test for hair loss relief
  • Evaluation of hair gloss
  • Evaluation of hair volume
  • Evaluation of hair elasticity
  • Evaluation of hair damage improvement
  • Evaluation of durability of hair coloring
  • Evaluation of hair moisturization
  • Evaluation of hair softness
  • Evaluation of hair tensile strength
  • Evaluation of hair protein penetration
  • In vivo test for dead skin cells in the scalp
  • In vivo test for scalp sebum
  • In vivo test for scalp moisturization
  • In vivo test for scalp elasticity
  • In vivo test for scalp cleansing power
  • In vivo test for scalp temperature
  • In vivo test for scalp blood flow

Efficacy Evaluation of Cosmetics (Others) 

  • In vivo test for halitosis inhibitory effect
  • In vivo test for evaluation of teeth whitening (marketing)
  • In vivo test for feminine washes
  • In vivo test for antibacterial hand washes
  • In vivo test for electroencephalogram (EEG test)

*Main test : In vivo testy for the evaluation of skin absorption (Raman spectroscopy)

Safety Evaluation of Cosmetics 

  • In vivo primary irritation test
    (PIT)
  • In vivo cumulative irritation test
    (CIT)
  • In vivo repeated insult patch test
    (RIPT)
  • In vivo non-comedogenic test
  • In vivo test for the evaluation of sensitive skin (in-use test)
  • In vivo eye irritation test

In Vitro Evaluation (Raw Materials) 

  • Antioxidant test (DPPH)
  • Antioxidant test (ABTS)
  • Antioxidant test (SOD)
  • Measurement test for total polyphenol content
  • ORAC index test (evaluation of finished product)
  • ROS inhibition test
  • Cytotoxicity test
  • Cell migration test
  • Cell viability test using dermal papilla cells
  • 5a-reductase expression inhibition test
  • Collagen production test
  • Collagenase activity inhibition test
  • Elastase activity inhibition test
  • Elastin production test
  • Melanin production inhibition test
  • Tyrosinase activity inhibition test
  • DOPA oxidation reaction inhibition test
  • Nitric oxide (NO) measurement test
  • Inflammation and skin barrier caused by fine dust
  • Measurement test of factor mRNA expression level
  • TARC inhibition
  • ELISA assay
  • Luciferase test
  • RT-PCR & RT-qPCR
  • Western blot
  • Immunofluorescence staining test
  • 3T3 NRU phototoxicity test
  • Skin irritation using artificial skin
  • Alternative test (non-GLP)
  • Inflammation-related factor test
  • Moisture-related factor test
  • Barrier-related factor test
  • Hair loss-related factor test